Effect of daily cleaning with chlorhexidine on the incidence of contamination of blood cultures in the critical patient
| Autor: | M. Mariné-Cabré, J. Riba-Reig, P. Garrido-Benedicto, R. Molina-Chueca, E. Farré-Termens, P. Cueto-Quintana |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Incidence (epidemiology) Significant difference Chlorhexidine Odds ratio Intervention group 030501 epidemiology Contamination Surgery 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Statistical analysis Blood culture 030212 general & internal medicine 0305 other medical science business medicine.drug |
| Zdroj: | Enfermería Intensiva (English ed.). 28:97-104 |
| ISSN: | 2529-9840 |
| DOI: | 10.1016/j.enfie.2017.03.001 |
| Popis: | Objective To evaluate the efficacy of daily cleaning with 4% chlorhexidine-impregnated sponges in decreasing contamination of blood cultures in critically-ill patients. Material and methods Prospective, quasi-experimental, longitudinal, single-centre trial. During 24 months (April 2013 to March 2015), we analysed 237 patients who fulfilled the inclusion criteria, divided into 2 groups: one underwent daily cleaning with common soap (control group, n = 108), and the other with chlorhexidine (intervention group, n = 109). Demographic variables, pathology group, severity scores, ICU and hospital length of stay and mortality, and time passed since cleaning to blood culture extraction were included. Results Statistical analysis showed a higher proportion of contaminated blood cultures during the control group period in contrast with the intervention group period (15 vs. 6.3%), with a significant difference: 9.23% (CI 95%: 1.34–16.7%), with an odds ratio of 2.73 (CI 95%: 1.13–6.63). Surveillance analysis showed lower probability of blood culture contamination within the 18 h following daily cleaning. Cleaning without chlorhexidine increased contamination of blood cultures (HR: 3.05; CI 95%: 1.14–8.12). Conclusions The use of 4% chlorhexidine-impregnated sponges for daily cleaning of critically-ill patients decreases blood culture contamination incidence and its protection lasts for almost 18 h. |
| Databáze: | OpenAIRE |
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