Hiperpigmentación cutánea secundaria a déficit de vitamina B12 en un lactante
| Autor: | María Marta Buján, María C Viada Pelaez, Andrea B Cervini |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Anemia business.industry Cutaneous hyperpigmentation nutritional and metabolic diseases Neutropenia medicine.disease Hyperpigmentation Cobalamin Dermatology Hypotonia 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Pediatrics Perinatology and Child Health polycyclic compounds medicine 030212 general & internal medicine Vitamin B12 medicine.symptom business |
| Zdroj: | Archivos Argentinos de Pediatria. 118 |
| ISSN: | 0325-0075 |
| Popis: | Cutaneous hyperpigmentation is a rare clinical feature of vitamin B12 (cobalamin) deficiency. The cause is unknown and there are different hypothesis about the pathogenesis of the hyperpigmentation. We report the case of an 8-month-old girl, with history of neuromadurative delay, hypotonia, anemia and neutropenia, who was referred to our Service by brownish hyperpigmentation on her hands and feet of 3 months of evolution. Based on the clinical suspicion of vitamin B12 deficiency, we performed a laboratory dosage that showed decreased levels of cobalamin, reason for which replacement therapy was indicated. It highlights the importance of the presumption of vitamin B12 deficiency as a cause of cutaneous hyperpigmentation and its rapid resolution after the establishment of the appropriate treatment. |
| Databáze: | OpenAIRE |
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