| Popis: |
The purpose of this study is to determine the prognostic value of factor signs for the effectiveness of anticoagulant and antiplatelet therapy in patients with severe COVID-19. Materials and methods: The frequency of cerebrovascular complications in severe COVID-19, the background of comorbid conditions of the cardiovascular continuum, the levels of hemo stasis and inflammation markers were studied. Results: With a sum of prognostic indicators equal to 2.7, the probability of developing cere brovascular complications is less than 1 %. With a prognostic indicator equal to 34.41, the probability of developing cerebrovascular complications approaches 100 %. Conclusions: The proposed prognostic scale, which takes into account the pathogenetic features of the relationship between markers of inflammation and coagulation, should be used in the treatment of patients with severe COVID-19 to identify the cohort of patients at high risk of developing cerebrovascular complications by summing the prognostic indicators depending on the presence of comorbid conditions of the cardiovascular continuum and the levels of markers of inflammation and thrombosis. |
