Lysophosphatidic acid and human erythrocyte aggregation

Autor:	Yu. A. Sheremet'ev, G. Ya. Levin, A. N. Popovicheva
Rok vydání:	2014
Předmět:	Rouleaux Echinocyte Cell Biology Biology Erythrocyte aggregation Microvesicles Cell biology chemistry.chemical_compound Autologous plasma Mechanism of action chemistry Lysophosphatidic acid medicine Human erythrocytes medicine.symptom
Zdroj:	Cell and Tissue Biology. 8:237-243
ISSN:	1990-5203 1990-519X
DOI:	10.1134/s1990519x14030110
Popis:	The effects of lysophosphatidic acid on the morphology and aggregation of human erythrocytes has been studied. Morphology of erythrocytes and their aggregates were studied by light microscopy. It has been shown that lysophosphatidic acid changes the shape of red blood cells: diskocyte become echinocytes. Aggregation of red blood cells (rouleaux) was significantly reduced in autoplasma. At the same time there is a strong aggregation of echinocytes. This was accompanied by the formation of microvesicles. Adding normal plasma to echinocytes restores shape and aggregation of red blood cells consisting of "rouleaux". A possible mechanism of action of lysophosphatidic acid on erythrocytes is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9b423ef213d926d22b415bcaaeed82d0 https://doi.org/10.1134/s1990519x14030110 Zobrazit plný text záznamu Full text from SpringerLink