Post-mating Refractoriness in Drosophila melanogaster Depends Upon Ecdysis Triggering Hormone Signaling
| Autor: | Matthew Meiselman, Michael E. Adams, Anindya Ganguly, Anupama Dahanukar |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
animal structures
biology Courtship display media_common.quotation_subject fungi biology.organism_classification Cell biology Courtship Mate choice Juvenile hormone behavior and behavior mechanisms Pheromone Drosophila melanogaster Corpus allatum Mating reproductive and urinary physiology media_common |
| DOI: | 10.1101/2021.10.29.466485 |
| Popis: | An individual’s decision to engage in courtship depends on external cues from potential mates and internal cues related to maturation, health, and experience. Hormones allow such information to be conveyed to distal tissues in a coordinated fashion. Here, we show Ecdysis-Triggering Hormone (ETH) is a regulator of male courtship in Drosophila melanogaster, and critical for mate choice and courtship inhibition after the completion of copulation. Preventing ETH release increases male-male courtship and decreases post-copulation courtship inhibition (PCCI). Such aberrant male courtship behavior in ETH-deficient males appears to be the consequence of inabilityto integrate pheromone cues into decision making. Silencing of ETH receptor (ETHR) in GR32A-expressing neurons leads to reduced ligand sensitivity and elevated male-male courtship. We find OR67D is critical for suppression of courtship after mating, and ETHR silencing in OR67D-expressing neurons, and GR32A-expressing neurons to a lesser degree, elevates post-copulation courtship. Finally, ETHR silencing in the corpus allatum increases post-copulation courtship; treatment of with juvenile hormone analog partially restores normal post-mating behavior. ETH, a stress-sensitive reproductive hormone, appears to coordinate multiple sensory modalities to guide Drosophila male courtship behaviors, especially after mating. |
| Databáze: | OpenAIRE |
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