Cardiac Modeling for Multisystem Inflammatory Syndrome in Children (MIS-C, PIMS-TS)
| Autor: | Jamie Weller, Radomir Chabiniok, Tarique Hussain, Kavita Sharma, Gerald F. Greil, Mohamed Abdelghafar Hussein, Jeffrey S. Kahn, Rebecca Waugh |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Inpatient stay Pharmacological therapy business.industry Pharmacological management Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) After discharge medicine.disease Intensive care unit Pathophysiology law.invention law Heart failure medicine Intensive care medicine business |
| Zdroj: | Functional Imaging and Modeling of the Heart ISBN: 9783030787097 FIMH |
| DOI: | 10.1007/978-3-030-78710-3_42 |
| Popis: | Cardiovascular data of 8 patients with Multisystem Inflammatory Syndrome in Children (MIS-C), caused by an aberrant reaction of immune system to the SARS-CoV-2 coronarovirus, were retrospectively analyzed by using patient-specific biomechanical modeling. The first goal was to increase the understanding of the pathophysiology of the cardiovascular involvement in MIS-C, during the inpatient stay at Intensive Care Unit and after discharge from the hospital. Secondly, hypothetical action of various types of pharmacological therapy was tested in silico using the created patient-specific models, aiming to contribute into the optimal pharmacological management during the acute stage of MIS-C. |
| Databáze: | OpenAIRE |
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