A Straightforward Synthesis of (3S)-4-Methoxybutane-1,3-diol and its Use as Chiral Auxiliary for the Preparation of (pS)-1-(Diphenylphosphino)-2-formyl-1′,2′,3′,4′,5′-pentamethylferrocene

Autor:	Felix M. Geisler, Guenter Helmchen
Rok vydání:	2006
Předmět:	chemistry.chemical_compound Chiral auxiliary Hydrolysis chemistry Ferrocene Organic Chemistry Diol Acetal Enantioselective synthesis Organic chemistry Medicinal chemistry Catalysis
Zdroj:	Synthesis. 2006:2201-2205
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-2006-942415
Popis:	(3S)-4-Methoxy-butane-1,3-diol (S)-4, an important auxiliary for the synthesis of planar-chiral metallocenes, has been obtained from (S)-1,2,4-butanetriol via formation of an isomerically pure acetal of p-nitrobenzaldehyde, O-methylation and hydrolysis. Diol (S)-4 was used in a synthesis of the new planar-chiral ferrocene ({pS)-1-(diphenylphosphiiio)-2-formyl-1'},2',3',4',5'-pentamethylferrocene ({pS)-9.}
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9b268d6441a6a935d748f5d1695c7c2f https://doi.org/10.1055/s-2006-942415 Zobrazit plný text záznamu