Investigation of the effects of chemotherapy on trace element contents in the nails in patients with colorectal cancer
| Autor: | Anh Tuan Tran, Dong Van Nguyen, Dung Manh Ho, Loan Thi Hong Truong, Binh Thanh Dinh, Phuong Truc Huynh, Hanh Van Nguyen, Linh Thi Truc Nguyen |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Colorectal cancer Health Toxicology and Mutagenesis medicine.medical_treatment 010403 inorganic & nuclear chemistry 01 natural sciences Gastroenterology Analytical Chemistry Internal medicine medicine Radiology Nuclear Medicine and imaging In patient Spectroscopy Chemotherapy business.industry Significant difference Public Health Environmental and Occupational Health Trace element Healthy subjects medicine.disease Pollution 0104 chemical sciences Cancer treatment medicine.anatomical_structure Nuclear Energy and Engineering Nail (anatomy) business |
| Zdroj: | Journal of Radioanalytical and Nuclear Chemistry. 328:1173-1180 |
| ISSN: | 1588-2780 0236-5731 |
| Popis: | The aim of this study was to evaluate the effects of cancer treatment with chemotherapy for the trace elements in nails of patients with colorectal cancer. The contents of trace elements in the nails of 102 patients with colorectal cancer (including treated and untreated) and 60 healthy subjects were analyzed using k0-standardization method of neutron activation analysis. All participants aged between 32 and 76. Result of this study showed that the contents of nine trace elements (As, Br, Co, Cr, Hg, Fe, Sc, Se, and Zn) in the nails were measured. Furthermore, this study showed that there was significant difference in the contents of the elements Fe, Se, and Zn in both colon and rectal cancer patient groups between untreated and treated subjects with chemotherapy. We conclude that the contents of Fe, Se, and Zn in the nail samples may be used to evaluate of the colorectal cancer risk, and they may be affected by chemotherapy. |
| Databáze: | OpenAIRE |
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