The Information Transmission from the Nucleobase Drives the Sugar-Phosphate Backbone Conformation in the Nucleotide Wire

Autor: Jyoti Chattopadhyaya, C. Thibaudeau
Rok vydání: 1998
Předmět:
Zdroj: Nucleosides and Nucleotides. 17:1589-1603
ISSN: 0732-8311
DOI: 10.1080/07328319808004691
Popis: We herein present our results showing that a simple mononucleotide block actually acts as a wire. This is evidenced by the fact that any change of the electronic character of the nucleobase is transmitted to drive the sugar conformation, which in turn dictates cooperatively the preferred orientation of the phosphate backbone.
Databáze: OpenAIRE