The role of the thalamus in human reinforcement learning

Autor: Antoine Collomb-Clerc, Maëlle C. M. Gueguen, Minotti Lorella, Kahane Philippe, Navarro Vincent, Bartolomei Fabrice, Carron Romain, Regis Jean, Chabardès Stephan, Stefano Palminteri, Julien Bastin
Rok vydání: 2022
DOI: 10.1101/2022.11.23.517731
Popis: Although the thalamus is supposed to be involved in reinforcement-based decision-making, there is no direct evidence regarding the involvement of this subcortical structure in humans. To fill this gap, we leveraged rare intra-thalamic electrophysiological recordings in patients and found that temporally structured thalamic oscillations encode key learning signals. Our findings also provide neural insight into the computational mechanisms of action inhibition in punishment avoidance learning.
Databáze: OpenAIRE