The Predictability of Lymph Node Metastasis in Patients with Endometrial Cancer
| Autor: | M. Hakan Yetimalar, Askin Yildiz, Sumeyra Tatar, Seyran Yiğit, Derya Kilic Sakarya, Burcu Kasap, Hayri Aksüt, Aykut Özcan |
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| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Turkiye Klinikleri Journal of Medical Sciences. 33:1028-1036 |
| ISSN: | 2146-9040 1300-0292 |
| DOI: | 10.5336/medsci.2012-31986 |
| Popis: | Objective: The aim of this study was to predict lymphatic involvement in endometrial cancer patients using clinicopathological variables in patients treated with surgical staging. Material and Methods: A retrospective chart review was performed in 147 women with pathologically proven endometrial carcinoma (EC) who were treated between January 2006 and January 2011. Surgically staged 125 patients were included in this study. We choose the patients who underwent surgical staging including washing cytology, total abdominal hysterectomy, bi - lateral salpingo-oophorectomy, and pelvic lymph node (PLN) and para-aortic lymph node (PALN) dissection. The depth of tumor invasion, cervical extension and the tumor diameter were intraoperatively assessed via fresh frozen sections of the removed uterus. Demographic data, preoperative and postoperative variables were evaluated for association with any lymph node (LN) metastasis. Results: The medical records of 125 patients were eligible for analysis. The presence of LN metastasis was significantly associated with the patient's age (p=0.016) and but not with body mass index (p=0.288). Preoperative findings such as atypical cells in smear (p=0.001), computed tomog - raphy (CT) features of malignancy (p=0.014), ultrasonographic findings related with malignancy (p=0.011), pres - ence of myometrial invasion on CT (p=0.011), preoperative serum CA125 level (p |
| Databáze: | OpenAIRE |
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