Tungstosulfonic acid-catalyzed green synthesis and bioassay of α-aminophosphonates

Autor: Santhisudha Sarva, Balaji Hari, Suresh Reddy Cirandur, Balaji Meriga, Mohan Gundluru, Sreekanth Tellamekala, Murali Sudileti
Rok vydání: 2019
Předmět:
Zdroj: Monatshefte für Chemie - Chemical Monthly. 150:1101-1109
ISSN: 1434-4475
0026-9247
DOI: 10.1007/s00706-019-2385-1
Popis: An eco-friendly green synthetic procedure was accomplished through the one-pot three-component synthesis of α-aminophosphonates having –CF3 moiety in good to excellent yields, under ultrasonication and solvent-free conditions in the presence of tungstosulfonic acid as an efficient, reusable, heterogeneous solid acid catalyst. All the title compounds were evaluated for their antioxidant activity using DPPH, H2O2 methods and antimicrobial activity by disc diffusion method. The bio-activity revealed that all the title compounds showed significant antioxidant and antimicrobial activities.
Databáze: OpenAIRE