A New Efficient Synthetic Method for 3-Iodothyronamine and Its Potent Hypothermic Efficacy

Autor:	Young-Kyu Song, Chan-Moon Chung, Ye-Ji Lim, Su-Yeon Jeon, Inho Choi, Joong-Gon Kim, Hyunwoo Ju
Rok vydání:	2011
Předmět:	3-Iodothyronamine chemistry.chemical_compound chemistry Yield (chemistry) Animal study General Chemistry Combinatorial chemistry
Zdroj:	Chinese Journal of Chemistry. 29:2205-2208
ISSN:	1001-604X
DOI:	10.1002/cjoc.201180382
Popis:	We developed a new efficient synthetic method for a 3-iodothyronamine (T1AM) that has advantages of less synthetic steps and much higher overall yield compared to those in the conventional method. Our animal study showed that T1AM synthesized by the method exerted a potent hypothermic effect in non-hibernator mice.
Databáze:	OpenAIRE
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