Catalytic Regioselective C–H Acetoxylation of Arenes Using 4,6-Dimethoxy-1,3,5-triazin-2-yloxy as a Removable/Modifiable Directing Group

Autor:	Yilei Wang, Tian Li, Cuiyu Jiang, Linhua Song, Na Li, Zhihua Peng, Zhi Yu
Rok vydání:	2017
Předmět:	Pyrocatechols 010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Regioselectivity 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis Inorganic Chemistry Group (periodic table) Physical and Theoretical Chemistry
Zdroj:	Organometallics. 36:2826-2831
ISSN:	1520-6041 0276-7333
Popis:	One of the major current challenges in the field of C–H functionalization is the development of new removable/modifiable directing groups (DGs). We report here the 4,6-dimethoxy-1,3,5-triazin-2-yloxy group as a new readily removable/modifiable DG for the regioselective acetoxylation of 2-(aryloxy)-4,6-dimethoxy-1,3,5-triazine. This developed phenol-derived DG can be easily removed to offer synthetically versatile pyrocatechols or converted into a useful biphenyl skeleton. In addition, the acetoxylation of 2-(aryloxy)-4,6-dimethoxy-1,3,5-triazine offers a new avenue to synthesize polysubstituted s-triazine derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9ab1a2464397fb4099bf95a8d04393d6 https://doi.org/10.1021/acs.organomet.7b00314 Zobrazit plný text záznamu