Ruthenium-catalyzed Selective Monoamination of Vicinal Diols
| Autor: | Dirk Hollmann, Lorenz Neubert, Kathleen Mevius, Sebastian Imm, Sebastian Bähn, Dirk Michalik, Matthias Beller, Annegret Tillack |
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| Rok vydání: | 2009 |
| Předmět: |
inorganic chemicals
Reaction conditions organic chemicals General Chemical Engineering chemistry.chemical_element Catalysis Ruthenium chemistry.chemical_compound General Energy chemistry Side product Environmental Chemistry Organic chemistry General Materials Science Ethylene glycol Vicinal Amination Pyrrole |
| Zdroj: | ChemSusChem. 2:551-557 |
| ISSN: | 1864-564X 1864-5631 |
| Popis: | The monoamination of vicinal diols in the presence of in situ generated ruthenium catalysts has been investigated. Among the various phosphines tested in combination with [Ru(3)(CO)(12)], N-phenyl-2-(dicyclohexyl-phosphanyl)pyrrole showed the best performance. After optimization of the reaction conditions this system was applied to different secondary amines and anilines as well as a number of vicinal diols. With the exception of ethylene glycol, monoamination of the vicinal diols occurred selectively and the corresponding amino alcohols were obtained in good yields, producing water as the only side product. |
| Databáze: | OpenAIRE |
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