A New and Convergent Synthesis of (2S)-7-(4,4‘-Bipiperidinylcarbonyl)-2,3,4,5- tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetic Acid Using a Palladium-Catalysed Aminocarbonylation Reaction

Autor:	and Timothy C. Walsgrove, Etridge Stephen K, Andrew S. Wells, Jerome F. Hayes
Rok vydání:	1998
Předmět:	Benzodiazepine Hydrochloride medicine.drug_class Organic Chemistry Convergent synthesis chemistry.chemical_element chemistry.chemical_compound Acetic acid chemistry medicine Moiety Organic chemistry Physical and Theoretical Chemistry Palladium
Zdroj:	Organic Process Research & Development. 3:60-63
ISSN:	1520-586X 1083-6160
Popis:	Palladium-catalysed aminocarbonylation of a 7-bromo- or 7-iodo-1,4-benzodiazepine with N-Cbz-4,4‘-bipiperidine hydrochloride efficiently introduced the 7-(4,4‘-bipiperidinylcarbonyl) moiety of (2S)...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9a85bca4f538d8a6ca64cfbc5aa93167 https://doi.org/10.1021/op980068n Zobrazit plný text záznamu