Popis: |
• The brain and the immune system are the two major adaptive systems of the body. There is crosstalk between these two systems, which allows for maintaining homeostasis. • There is a large body of evidence that documents the effects of stress on a variety of components of the immune response at the systemic level as well as cutaneous immunity. • Stress can render the host more susceptible to bacterial infections and the development of cancer. • Emotional stressors have been anecdotally linked to the development or exacerbation of a number of skin diseases (for example, acne, vitiligo, alopecia areata, lichen planus, seborrheic dermatitis, herpes infections). • The role of stress in atopic dermatitis and psoriasis is well studied, and has established the adverse effects of stress on the clinical course of both diseases. • There is definitely a brain–skin connection that can translate emotional stressors into biochemical mediators that can result in adverse effects on dermatologic diseases. |