Pharmacognostic and pharmacological study of liquid extract of Crataegus Submollis Sarg. Flowers

Autor: Viktoriya V. Stenyaeva, Anna V. Kurkinа, Ilnur Kh. Shaikhutdinov, Olga Evgenevna Pravdivtseva, Tat'yana Vladimirovna Morozova, V. A. Kurkin, Elena N. Zaitceva
Rok vydání: 2020
Předmět:
Zdroj: Aspirantskiy Vestnik Povolzhiya. 19:160-164
ISSN: 2410-3764
2072-2354
DOI: 10.17816/2072-2354.2019.19.3.160-164
Popis: The flowers and fruits of various species of the hawthorn genus (Crataegus L.) are widely used in domestic and foreign medical practice as cardiotonic agents. A perspective species for collecting of the raw material is Crataegus submollis Sarg. It was determined that 70% ethanol is an optimal extragent for the extraction of flavonoids from Crataegus submollis Sarg. flowers. The content of the total flavonoids in terms of hyperoside in the liquid extract of Crataegus submollis Sarg. flowers is 0,24 0,01%. It was established that liquid extract of Crataegus submollis Sarg. with using of 70% ethanol in case of a single intragastric administration in the dose of 100 l/kg shows significant antidepressant activity. Crataegus submollis Sarg. flowers are the perspective medicinal plant raw materials.
Databáze: OpenAIRE