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Aim: The study is aimed at investigating the antinutritive effects of aqueous root extract of Moringa oleifera on haematological indices following sub-chronic consumption of alcohol in Wistar rats. Methods and Materials: Thirty (30) experimental rats weighing 100-120 g were randomly divided into 6 groups of 5 rats each. Group 1, the normal control group was given just rat feed and water, group 2, negative control was administered alcohol only (1.5 ml/kg body weight), rats in group 3, 4 and 5 received combined administration of alcohol 1.5 ml/kg body weight and 200, 400 and 600 mg/kg body weight of aqueous root extract of Moringa oleifera respectively, group 6 rats were administered 250 mg/body weight of extract only. At the end of fourteen days (14) the experimental rats were then sacrificed, and blood was collected for haematological analysis. Results: The result obtained shows a dose-dependent response in almost all the parameters, white blood cell (WBC) count increases significantly(P |
