Association between cannabis and psychiatric hospitalization

Autor: R.S. Kahn, C. D. Schubart, Marco P. Boks, Elemi J. Breetvelt, Iris E. C. Sommer, W. A. van Gastel, Rolf H.H. Groenwold, Roel A. Ophoff
Rok vydání: 2010
Předmět:
Zdroj: Acta Psychiatrica Scandinavica. 123:368-375
ISSN: 0001-690X
DOI: 10.1111/j.1600-0447.2010.01640.x
Popis: Objective: To investigate the relationship between cannabis use and mental health. Method: A cross‐sectional analysis in a sample of 17 698 individuals with a mean age of 22 years (SD: 4.2). Participants provided information on the amount and initial age of cannabis use and history of psychiatric hospitalizations through a web‐based questionnaire. To quantify Δ9‐tetrahydrocannabinol exposure, we operationalized cannabis use as the amount of money spent on cannabis per week over the last month. The odds ratio of having a history of psychiatric hospitalizations was the primary outcome measure. Results: We found a dose-response relationship between the amount of cannabis use and the odds for psychiatric hospitalization. Adjusted odds ratios for hospitalization increased with the amount of cannabis consumed from 1.6 (95% CI: 1.1-2.3) in incidental users to 6.2 (95% CI: 4.3-8.9) in heavy users (>€25/week). Our data suggested that concomitant drug use was an intermediate factor. Exposure to cannabis before the age of 12 years was found to carry a 4.8 (95% CI: 2.9-7.8) times increased odds for past psychiatric hospitalizations. Conclusion: We conclude that early and heavy uses of cannabis are each and independently associated with poor mental health in its users.
Databáze: OpenAIRE
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