RecurrentStaphylococcus aureusabscess and fatal pneumococcal septicemia due to IRAK-4 deficiency

Autor:	Tadanori Nakatsu, Koichi Shichijo, Ayumi Tomimoto, Takeshi Ogose, Mari Kubota, Takako Taniguchi, Akiyoshi Takahashi, Tsutomu Watanabe, Rieko Kondo, Yoshio Urano
Rok vydání:	2015
Předmět:	business.industry Staphylococcal infections medicine.disease medicine.disease_cause Sepsis Fungal disease Skin Abscess Staphylococcus aureus Pneumococcal septicemia Pediatrics Perinatology and Child Health Immunology medicine Abscess business Meningitis
Zdroj:	Pediatrics International. 57:1166-1169
ISSN:	1328-8067
Popis:	We describe the case of an infant with recurrent episodes of staphylococcal skin abscess and subsequent lethal pneumococcal meningitis/septicemia due to interleukin-1 receptor-associated kinase 4 (IRAK-4) deficiency. In this case, systemic signs of inflammatory response were poor and delayed. Among all other reported cases of IRAK-4 deficiency, none involved severe viral or fungal disease, and the range of infecting bacteria was narrow.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9a393f042dbb005d5296f1f59c50aaec https://doi.org/10.1111/ped.12722 Zobrazit plný text záznamu Plný text