Activity determination of 68Ge/68Ga by means of 4πβ(Č)-γ coincidence counting
| Autor: | Justyna Marganiec-Gałązka, Ole Nähle, Karsten Kossert |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Physics
Radionuclide Radiation medicine.diagnostic_test Isotope Detector Liquid scintillation counting Analytical chemistry 010403 inorganic & nuclear chemistry 01 natural sciences 030218 nuclear medicine & medical imaging 0104 chemical sciences Nuclear physics 03 medical and health sciences 0302 clinical medicine Positron emission tomography Annihilation radiation medicine Coincidence counting Arithmetic mean |
| Zdroj: | Applied Radiation and Isotopes. 134:240-244 |
| ISSN: | 0969-8043 |
| DOI: | 10.1016/j.apradiso.2017.06.027 |
| Popis: | Germanium-68 is an important radionuclide since it is used to generate its daughter 68Ga which is frequently used for positron emission tomography (PET). In addition, 68Ge/68Ga sources are often used as surrogates for short-lived PET isotopes when calibrating instruments. In this work, 4πβ(C)-γ coincidence counting was used to determine the activity concentration of a 68Ge/68Ga solution. The presented measurements were made by means of a new PTB-custom-built 4π(LS)β-γ coincidence counting system, where a liquid scintillation detector in the β channel can also be used as a Cerenkov counter, and a NaI(Tl) crystal detects annihilation radiation. The arithmetic mean of two results (from double ND and triple NT coincidences in the β channel) was adopted as the final result for the activity concentration of the solution under study. The overall relative uncertainty was estimated to be 0.82% and the uncertainty consideration as well as details about the measurement and the analysis are discussed. The measurements were carried out within the scope of the international CCRI(II)-K2.Ge-68 comparison. |
| Databáze: | OpenAIRE |
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