Synthesis and antiviral activity of 4-quinolinecarboxylic acid hydrazides

Autor:	P. L. Trakhtenberg, R. S. Belen'kaya, M. N. Zemtsova, E. I. Boreko, A. V. Zimichev
Rok vydání:	2008
Předmět:	Pharmacology chemistry.chemical_compound chemistry Virus type Stereochemistry Aryl Drug Discovery Pharmacology toxicology Nitro Substituent Ethyl ester Hydrazide
Zdroj:	Pharmaceutical Chemistry Journal. 42:571-573
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-009-0187-1
Popis:	Antiviral agents were sought by using ethyl esters of 2-R-4-quinolinecarboxylic acids to synthesize the corresponding aryl (heteryl) hydrazides. 2-Methyl-4-quinolinecarboxylic acid hydrazide was used to synthesize vinylogs containing a nitro group in the substituent. The resulting compounds were tested for antiviral activity against ECHO virus type 6.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9a00b1fff63854ebfeb06f7807722029 https://doi.org/10.1007/s11094-009-0187-1 Zobrazit plný text záznamu Plný text ve formátu PDF