Visible-light induced metal-free cascade Wittig/hydroalkylation reactions

Autor:	Pannan Miao, Liangming Rao, Ruining Li, Zhankui Sun, Xianfeng Lin
Rok vydání:	2021
Předmět:	Metal free Cascade Chemistry Indolizidine 209D Wittig reaction Environmental Chemistry One-Step Pollution Combinatorial chemistry Visible spectrum
Zdroj:	Green Chemistry. 23:1638-1641
ISSN:	1463-9270 1463-9262
DOI:	10.1039/d1gc00091h
Popis:	Cascade reactions are green and powerful transformations for building multiple carbon–carbon bonds in one step. Through a relay olefination and radical addition process, we were able to develop the cascade Wittig/hydroalkylation reactions induced by visible light. This metal-free radical approach features mild conditions, robustness, and excellent functionality compatibility. It allows access to saturated C3 homologation products directly from aldehydes or ketones. The synthetic utility of this method is demonstrated by a two-step synthesis of indolizidine 209D.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::99f906ee41bba7f3505cf233600e836d https://doi.org/10.1039/d1gc00091h Zobrazit plný text záznamu