Rituximab in IgM Nephropathy Resistant to Multiple Immunosuppressives: A Case Report

Autor: Dr. Md. Omar Faroque, Amit Bari, Sayed Fazlul Islam, KBM Hadiuzzaman, Rana Mokarram Hossain, Muhammad Nazrul Islam
Rok vydání: 2022
Předmět:
Zdroj: Scholars Journal of Medical Case Reports. 10:1266-1268
ISSN: 2347-6559
2347-9507
Popis: Immunoglobulin M (IgM) Nephropathy is a primary glomerulonephritis, characterized by predominant IgM deposition on direct immunofluorescence (DIF) microscopy. Long considered to be similar to minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS), it is now considered to be a separate entity with unique epidemiology, clinical presentation, biopsy findings, treatment response and prognosis. Although steroid is the first line treatment, there is a high degree of steroid resistance. Other immunosuppressive egents have not been quite effective. Rituximab is an emerging treatment option. We present a 40-year-old man with IgM Nephropathy in whom Rituximab proved to be a highly effective treatment.
Databáze: OpenAIRE