Flow Cytometric Evaluation on Deparaffinized Material in Prostatic Carcinoma

Autor:	T. Prayer Galetti, R. Salmaso, R. Bertoldin, S. Blandamura, M. Panozzo, L. D'Arrigo, Fabio Vianello, G. Costantin, Filiberto Zattoni
Rok vydání:	1993
Předmět:	Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Prostatectomy medicine.medical_treatment Cancer General Medicine urologic and male genital diseases medicine.disease Flow cytometry Carcinoma Medicine business Grading (tumors) Dna ploidy Prostatic tissue
Zdroj:	Urologia Journal. 60:175-178
ISSN:	1724-6075 0391-5603
DOI:	10.1177/039156039306000210
Popis:	DNA nuclear ploidy determined by flow cytometry was evaluated from prostatic tissue in 64 patients with prostatic cancer who had undergone radical prostatectomy. DNA ploidy was compared to tumour stage, tumour grading (Gleason score), PSA. DNA ploidy pattern was diploid in 46% and aneuploid in 54% of the tumours. Tumours pathologically staged B acc. to AUS were aneuploid in 25%, those staged C in 59% and those staged D in 66.6%. Aneuploidy was found in 36% of the tumours with Gleason score between 2 and 4, in 63% between 5 and 7 and in 45% between 8 and 10. Mean preoperative seric PSA was 34.3 ng/ml in diploid tumours and 39.8 ng/ml in aneuploid neoplasms. Our results suggest no relationship between tumour stage, grade and preoperative PSA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::99e0945d3eaffcc032a82514e6406488 https://doi.org/10.1177/039156039306000210 Zobrazit plný text záznamu