Numerical Modeling of Electroporation Process Using Endocardial Catheter

Autor: Radoslav Cipin, Veronika Novotna, Zdenek Starek, Martin Pešl, Dalibor Cervinka
Rok vydání: 2020
Předmět:
Zdroj: 8th European Medical and Biological Engineering Conference ISBN: 9783030646097
Popis: This paper is about electroporation using an endocardial catheter. It is focused on numerical modeling of the electroporation process inspired by in vivo experiment. Two electroporation models are compared; model with electric conductivity dependent and independent on the electric field intensity. Further, it also demonstrates the effect of the flowing blood on obtained results. The electroporation effect in the homogeneous tissue is symmetrical unlike the effect in the inhomogeneous tissue. Blood flowing around the application electrode cools down the tissue but takes also majority of the current. The treatment has to be either longer or use higher voltage. The temperature was 40.7 °C for the model with electric conductivity dependent on the electric field intensity vs 45 °C with independent electric conductivity. Comparison of the simulated and measured data is not part of this paper.
Databáze: OpenAIRE