Recurrence and prognosis of patients emergently hospitalized for acute esophageal variceal bleeding: A long-term cohort study
| Autor: | Koh Imbe, Hourin Cho, Junichi Akiyama, Masao Kobayakawa, Chizu Yokoi, Masashi Mizokami, Mikio Yanase, Takuro Shimbo, Hidetaka Okubo, Naoyoshi Nagata, Katsunori Sekine, Kazuhiro Watanabe, Shintaro Mikami, Toshiyuki Sakurai, Naomi Uemura |
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| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Cirrhosis Hepatology medicine.diagnostic_test Proportional hazards model business.industry Hazard ratio medicine.disease Gastroenterology Endoscopy 03 medical and health sciences 0302 clinical medicine Infectious Diseases 030220 oncology & carcinogenesis Internal medicine Hepatocellular carcinoma Cohort Risk of mortality medicine 030211 gastroenterology & hepatology business Cohort study |
| Zdroj: | Hepatology Research. 46:1338-1346 |
| ISSN: | 1386-6346 |
| Popis: | AIM To elucidate the rates of recurrence and mortality in acute esophageal variceal bleeding and the associated risk factors. METHODS A cohort of 174 patients emergently hospitalized for esophageal variceal bleeding was analyzed. All patients underwent endoscopic variceal ligation within 3 h of arrival. Comorbidities, vital signs, drug use, laboratory data, etiology, endoscopic findings, transfusion requirement, and follow-up endoscopy were assessed. Cox's proportional hazards model was used to estimate hazard ratios (HR). RESULTS Rebleeding was identified in 49 patients with a mean follow-up of 18 months. The cumulative rebleeding rate at 1 month, 1 year, and 5 years was 10.2%, 30.0%, and 51.0%, respectively. In multivariate analysis, independent risk factors for rebleeding were child-Pugh class C (HR 1.94; P = 0.027), alcoholic liver cirrhosis (HR 2.32; P = 0.01), and no follow-up endoscopy (HR 13.3; P |
| Databáze: | OpenAIRE |
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