| Popis: |
The article presents data on the antiseptic and disinfectant effect of the drug «Vitosept». The peculiarity of this biocidal product is that the active substance in it is high-purity sodium hypochlorite, obtained in a spe-cially designed diaphragm-free flow electrolyzer using isotonic sodium chlorite solution prepared in water purified by a separate technology. In the course of the conducted researches it was found out that the investigated remedy has the expressed bactericidal, fungicidal and sporocidal properties. Its high bactericidal activity against E. coli, S. aureus, P. aeruginosa has been established. There was a decrease in the number of microorganisms by 6.5-7.5 lg in the first 30 minutes of contact both in the presence of organic matter (5% bovine albumin B.S.A.) and in its ab-sence. Resistance of A. niger to «Vitosept», in the presence of high organic load (5% of bovine albumin-B.S.A.) allows to recommend a differentiated approach to the mode of disinfection in mycosis foci; to wipe twice with an interval of 15 minutes, and when immersed in 60 minutes to replace «Vitosept» and keep the items in solu-tion for 30 minutes. It was confirmed that when disinfecting objects contaminated with fungi, it is necessary to use higher concentrations of the studied drug and increase the duration of contact, in particular, the concen-tration should be maintained at 600 mg / l for more than three hours. The use of lower concentrations is not appropriate, because it requires a long period of action and does not guarantee the desired result. Increasing the temperature of «Vitosept» to 50 ° C and keeping it at this level for 30 minutes dramatically increases the sporicidal activity of the drug. In this case, the time required for sterilization is reduced several times. However, given the technical difficulties associated with heating, the use of the temperature factor can be considered as one of the possible options. |
