Prostaglandins and Platelet Aggregation in Vivo

Autor:	J Kloeze
Rok vydání:	1970
Předmět:	Electric stimulus Platelet aggregation In vivo Chemistry Anesthesia Biophysics Alpha (ethology) lipids (amino acids peptides and proteins) Hematology Rat brain Platelet thrombus circulatory and respiratory physiology
Zdroj:	Thrombosis and Haemostasis. 23:293-298
ISSN:	2567-689X 0340-6245
Popis:	SummaryIt was shown previously that prostaglandin E1 (PGE1) inhibits the aggregation of blood platelets in vitro whereas PGF1α does not; in vivo, PGE1 inhibits in rats the action of intravenously injected adenosine diphosphate. Locally administered PGE1 is found in the present experiment to inhibit in rats the formation and growth of platelet thrombi, induced by an electric stimulus in cortical veins. PGF1α appeared to be inactive.The morphology of platelet thrombi induced by an electric stimulus is shown. The probability of a primary role of erythrocytes in the formation of this type of thrombi is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::99ac42de5c1721fe0354234b1c68be18 https://doi.org/10.1055/s-0038-1654142 Zobrazit plný text záznamu