Intraoperative floppy-iris syndrome associated with duloxetine
| Autor: | Nikolaos Kasimatis, Efterpi Chatzispasou, Nikolaos Varvayannis, Lampros Lamprou, Diana Verikokaki |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Intraoperative floppy iris syndrome Phacoemulsification Hyperplasia Cataract surgery medicine.disease Surgery 03 medical and health sciences Ophthalmology chemistry.chemical_compound 0302 clinical medicine chemistry Tamsulosin 030221 ophthalmology & optometry Medicine Duloxetine Major depressive disorder Medical history 030212 general & internal medicine business medicine.drug |
| Zdroj: | JCRS Online Case Reports. 4:31-33 |
| ISSN: | 2214-1677 |
| Popis: | Intraoperative floppy-iris syndrome (IFIS) is an entity encountered during cataract surgery (phacoemulsification), affecting mainly male patients with a history of benign prostatic hyperplasia being treated with the α-1A adrenergic blocker tamsulosin. Weaker association with other α-1A selective and α-1 nonselective antagonists has been documented. Cases associated with the use of other drugs have also been reported. We present a female patient who had features of IFIS in both eyes during cataract surgery. She had an unremarkable medical history apart from major depressive disorder that was treated with duloxetine. Many reports of IFIS affecting patients of both sexes who were not treated with α-1 antagonists suggest a complex mechanism of the syndrome. The role of other receptors is discussed. Financial Disclosure None of the authors has a financial or proprietary interest in any material or method mentioned. |
| Databáze: | OpenAIRE |
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