The Effect of Dietary Linoleic Acid and Pectin on Lipoprotein and Apolipoprotein Al Concentrations in Rhesus Monkeys
| Autor: | Robert J. Heine, E. A. van der Veen, Louis M. Havekes, C.M. van Gent, Peter Koopman, J.A. Schouten |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics food.ingredient biology Pectin Serum lipid levels Cholesterol Linoleic acid Medicine (miscellaneous) Metabolism Serum lipoprotein levels chemistry.chemical_compound food Endocrinology chemistry Internal medicine biology.protein medicine lipids (amino acids peptides and proteins) Apolipoprotein A1 Lipoprotein |
| Zdroj: | Annals of Nutrition and Metabolism. 28:201-206 |
| ISSN: | 1421-9697 0250-6807 |
| DOI: | 10.1159/000176805 |
| Popis: | Medium term effects (3 months) on serum lipoprotein levels of a diet with a high P/S ratio (2.2) and a low P/S ratio (0.3) were investigated in 13 normolipoproteinemic rhesus monkeys. Both diets were studied with and without added gel-forming fibre, as pectin. Addition of pectin did not have major influences on serum lipid levels. Changing from a low to a high P/S diet resulted in a significant decrease of total cholesterol (23%) and LDL cholesterol (18%) levels, but also HDL cholesterol (23%) and apolipoprotein A1 (Apo A1; 13%) concentrations fell significantly. However, after 12 weeks on the high P/S diet, HDL cholesterol concentrations rose by 24%, not significantly different from the levels during the low P/S diet. We conclude that the medium-term effects of a high P/S diet are a decrease in LDL cholesterol with only a transient effect on HDL cholesterol. |
| Databáze: | OpenAIRE |
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