ChemInform Abstract: Bromination of 2-Thiazolylhydrazones

Autor: G. P. Andronnikova, Vadim A. Shevyrin, S. V. Usol'tseva
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 25
ISSN: 0931-7597
Popis: Bromination of the 4-carbethoxy- and 4-carboxy-2-thiazolylhydrazones of aldehydes and ketones occurs principally at the 5 position of the thiazole ring. In the case of aldehyde hydrazones an excess of bromine leads to substitution of the methine hydrogen atom and to intramolecular cyclization of the intermediate halohydrazone to 1,2,4-triazolo[3,4-b]thiazole.
Databáze: OpenAIRE