Cryochemical synthesis and antibacterial activity of hybrid nanocomposites based on dioxidine containing Ag and Cu nanoparticles incorporated in biopolymer cryostructurates
| Autor: | V. P. Shabatin, V. I. Lozinskii, O. I. Vernaya, Tatyana I. Shabatina, D. I. Khvatov, M. Ya. Mel’nikov, N. D. Zvukova, A. V. Nuzhdina, A. M. Semenov |
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| Rok vydání: | 2017 |
| Předmět: |
Cu nanoparticles
Nanocomposite Chemistry Infrared spectroscopy Sorption 02 engineering and technology General Chemistry engineering.material 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Transmission electron microscopy Proton NMR engineering Biopolymer 0210 nano-technology Antibacterial activity Nuclear chemistry |
| Zdroj: | Russian Chemical Bulletin. 66:2152-2156 |
| ISSN: | 1573-9171 1066-5285 |
| DOI: | 10.1007/s11172-017-1996-0 |
| Popis: | Cryochemical synthesis of hybrid nanocomposites based on the antibacterial drug, dioxidine, and metals (Ag, Cu) was performed. According to the data of H1 NMR, UV, and IR spectroscopy, low-temperature argon sorption, and transmission electron microscopy, met-als in these systems exist as Ag nanoparticles (with dimensions of 2—30 nm) or Cu nanoparti-cles (10—40 nm) involved in the bigger-sized particles of dioxidine with dimensions of 50—350 nm. These hybrid nanocomposites show the enhanced antibacterial activity towards the microbial cells Escherichia coli 52, Staphylococcus aureus 144, Mycobacterium cyaneum 98. The as-prepared drug nanocomposites are incorporated into spongy alginate cryostructurates. The feasibility of drug release from the biopolymer alginate carrier is proved and the related antibacterial activity is demonstrated. |
| Databáze: | OpenAIRE |
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