Dermal Anesthesia Using a Lidocaine Gel Patch for Pain of Human Growth Hormone (hGH) Self-injection and Relief of Anxiety
| Autor: | Motohiro Mishima, Mihoko Kodama, Tatsuhiko Kano, Masahiro Nakano, Osami Tsuzuki, Noritaka Iwatani, Teruhisa Miike |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
Lidocaine business.industry Endocrinology Diabetes and Metabolism Self injection Human growth hormone hgh Absorption (skin) medicine.disease Placebo Growth hormone deficiency Endocrinology Anesthesia Internal medicine Pediatrics Perinatology and Child Health medicine Anxiety medicine.symptom business hormones hormone substitutes and hormone antagonists medicine.drug Transdermal |
| Zdroj: | Clinical Pediatric Endocrinology. 3:113-116 |
| ISSN: | 1347-7358 0918-5739 |
| DOI: | 10.1297/cpe.3.113 |
| Popis: | We estimated the benefits of a transdermally applicable 10% lidocaine gel mixture with absorption promoter (glycyrrhetinic acid monohemiphthalate disodium: GA MHPh 2Na) for the self-injection of human growth hormone (hGH) to reduce injection distress in eight children with growth hormone deficiency (GHD). Pain rating scales upon both needle puncture and fluid injection of hGH were significantly lower with the lidocaine gel application than with the placebo. The use of the lidocaine gel application in hGH therapy can alleviate the pain of injection and accompanying anxiety, thus obtaining better compliance of children who need daily injections of hGH. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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