Synthesis of [35s]-labelled MK-0571, a potent antagonist of LTD4

Autor: Robert N. Young, D. R. D. Shaw, Robert Zamboni, Haydn W. R. Williams
Rok vydání: 1990
Předmět:
Zdroj: Journal of Labelled Compounds and Radiopharmaceuticals. 28:297-306
ISSN: 0362-4803
DOI: 10.1002/jlcr.2580280306
Popis: The synthesis of 5-[3-{2-(7-chloroquinolin-2-yl)ethenyl}-phenyl]-8-dimethylcarbamyl-4,6-[6-35S]dithiaoctanoic acid at a specific activity of 1350 Ci/mmol is reported. This compound is a reagent suited for selective affinity binding studies at the LTD4 receptor.
Databáze: OpenAIRE