Comparative analysis of iterative reconstruction algorithms with resolution recovery and time of flight modeling for 18F-FDG cardiac PET: A multi-center phantom study
Autor: | Michela Lecchi, Lucia Leva, Claudio Marcassa, Angelo Del Sole, Christian Bracco, Carlo Rodella, Domenico Lizio, Camilla Scabbio, Marco Brambilla, Roberta Matheoud, Orazio Zoccarato, Luca Indovina |
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Rok vydání: | 2016 |
Předmět: |
medicine.diagnostic_test
business.industry Iterative reconstruction 030204 cardiovascular system & hematology Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences Time of flight Cardiac phantom 0302 clinical medicine Cardiac PET Positron emission tomography medicine Radiology Nuclear Medicine and imaging Resolution recovery Cardiology and Cardiovascular Medicine Wall thickness Nuclear medicine business |
Zdroj: | Journal of Nuclear Cardiology. 24:1036-1045 |
ISSN: | 1532-6551 1071-3581 |
Popis: | The purpose of this study was to evaluate the image quality in cardiac 18F-FDG PET using the time of flight (TOF) and/or point spread function (PSF) modeling in the iterative reconstruction (IR). Three scanners and an anthropomorphic cardiac phantom with an insert simulating a transmural defect (TD) were used. Two sets of scans (with/without TD) were acquired, and four reconstruction schemes were considered: (1) IR; (2) IR + PSF, (3) IR + TOF, and (4) IR + TOF + PSF. LV wall thickness (FWHM), contrast between LV wall and inner chamber (C IC), and TD contrast in LV wall (C TD) were evaluated. Tests of the reconstruction protocols showed a decrease in FWHM from IR (13 mm) to IR + PSF (11 mm); an increase in the C IC from IR (65%) to IR + PSF (71%) and from IR + TOF (72%) to IR + TOF + PSF (77%); and an increase in the C TD from IR + PSF (72%) to IR + TOF (75%) and to IR + TOF + PSF (77%). Tests of the scanner/software combinations showed a decrease in FWHM from Gemini_TF (13 mm) to Biograph_mCT (12 mm) and to Discovery_690 (11 mm); an increase in the C IC from Gemini_TF (65%) to Biograph_mCT (73%) and to Discovery_690 (75%); and an increase in the C TD from Gemini_TF/Biograph_mCT (72%) to Discovery_690 (77%). The introduction of TOF and PSF increases image quality in cardiac 18F-FDG PET. The scanner/software combinations exhibit different performances, which should be taken into consideration when making cross comparisons. |
Databáze: | OpenAIRE |
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