Effect of Piper betle extract on anti-candidal activity, gelation time, and surface hardness of a short-term soft lining material

Autor: Jindaporn Puripattanavong, Juthatip Kumpanich, Widchaya Kanchanavasita, Trinuch Eiampongpaiboon, Somsak Chitmongkolsuk
Rok vydání: 2020
Předmět:
Zdroj: Dental Materials Journal. 39:1016-1021
ISSN: 1881-1361
0287-4547
DOI: 10.4012/dmj.2019-314
Popis: The purpose of this study was to evaluate anti-candidal activity, gelation time, and surface hardness of a short-term soft lining material incorporated with varying concentrations of Piper betle extract (0.25 to 20% w/w). Agar-diffusion assay was conducted to evaluate an inhibitory effect against Candida albicans. The gelation time was assessed and surface hardness was measured at 2 h and 7 days by Shore AO durometer. A soft liner containing at least 5% w/w of P. betle extract was observed the inhibitory effect against C. albicans. An increasing of P. betle concentrations provided larger inhibition zone. Incorporating 5% w/w of P. betle extract into the soft liner did not significantly alter its gelation time and surface hardness (ANOVA; p>0.05). The optimum composition at 5% w/w of P. betle extract can be used as an additive in the soft liner to provide the anti-candidal activity without significantly affect these two main properties.
Databáze: OpenAIRE