Synthesis of 1,4-enyne-3-ones via palladium-catalyzed sequential decarboxylation and carbonylation of allyl alkynoates
| Autor: | Weigao Hu, Jianxiao Li, Wanqing Wu, Huanfeng Jiang, Zun Li, Jia Zheng |
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| Rok vydání: | 2017 |
| Předmět: |
Enyne
010405 organic chemistry Chemistry Decarboxylation Isocyanide Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Combinatorial chemistry Reductive elimination 0104 chemical sciences Catalysis chemistry.chemical_compound Functional group Organic chemistry Carbonylation Palladium |
| Zdroj: | Organic Chemistry Frontiers. 4:1363-1366 |
| ISSN: | 2052-4129 |
| Popis: | Herein we describe a novel protocol for the rapid assembly of 1,4-enyne-3-ones from isocyanides and 1,6-enyne. During this process, two different types of C–C bonds were formed on the same isocyanide carbon atom via sequential decarboxylation, insertion of isocyanide, and reductive elimination. Moreover, this approach shows advantages of mild reaction conditions and excellent functional group compatibility. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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