| Autor: |
Jungyoup Han, Jianting Wang, Chong H. Ahn, Zhiwei Zou, Kyung A. Kang, Bin Hong, Junhai Kai |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Advances in Experimental Medicine and Biology ISBN: 9780387859972 |
| DOI: |
10.1007/978-0-387-85998-9_16 |
| Popis: |
A rapid and accurate diagnosis of acute myocardial infarction (AMI) is crucial for saving lives. For this purpose, we have been developing a rapid, automatic, point-ofcare, biosensing system for simultaneous four cardiac marker quantification. This system performs a fluorophore mediated immuno-sensing on optical fibers. To improve the sensitivity of the sensor, novel nanoparticle reagents enhancing fluorescence were implemented. Micro-electro-mechanical system (MEMS) technology was applied in the sensing chip development and automatic sensing operation was implemented to ensure a reliable and user-friendly assay. The resulting system is a point-of-care, automatic four cardiac marker sensing system with a 2 x 2.5cm sensing chip. An assay requires a 200 μ$L plasma sample and 15-minute assay time. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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