Chemoselective and Regiospecific Formylation of 1-Phenyl-1H-pyrazoles Through the Duff Reaction

Autor: Luciano M. Lião, Francine Pazini, Marcos N. Eberlin, C. H. A. de Oliveira, A. L. de Oliveira, Luiz Carlos da Cunha, V. de Oliveira, Fábio Oliveira, Catarina Viegas, Ricardo Menegatti, J. L. Paz, L. M. Mairink
Rok vydání: 2013
Předmět:
Zdroj: Synthetic Communications. 43:1633-1639
ISSN: 1532-2432
0039-7911
DOI: 10.1080/00397911.2012.657764
Popis: The synthesis of formylated 1-phenyl-1H-pyrazole derivatives under the Duff reaction conditions is reported. Our results indicate that 1-phenyl-1H-pyrazole systems containing electron-withdrawing and electron-donating substituents at the phenyl moiety react under the Duff reaction conditions to furnish formylated derivatives in good yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.
Databáze: OpenAIRE
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