A Systematic Evaluation of the Bleomycin A2 l -Threonine Side Chain: Its Role in Preorganization of a Compact Conformation Implicated in Sequence-Selective DNA Cleavage
Autor: | Hui Cai, Dale L. Boger, JoAnne Stubbe, Timothy M. Ramsey, Silvia T. Hoehn |
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Rok vydání: | 1998 |
Předmět: | |
Zdroj: | Journal of the American Chemical Society. 120:9139-9148 |
ISSN: | 1520-5126 0002-7863 |
Popis: | The preparation and examination of 3−7 are detailed and constitute analogues of deglycobleomycin A2 (2) containing systematic modifications in the l-threonine side chain. The studies revealed a sub... |
Databáze: | OpenAIRE |
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