| Autor: |
Tapio Kurki, Jorma Paavonen, Eeva-Marja Rutanen, Vilho Hiilesmaa, Minnamaija Kekki, Tytti Kärkkäinen |
| Rok vydání: |
2001 |
| Předmět: |
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| Zdroj: |
Acta Obstetricia et Gynecologica Scandinavica. 80:546-551 |
| ISSN: |
0001-6349 |
| DOI: |
10.1034/j.1600-0412.2001.080006546.x |
| Popis: |
Background. The aim of the study was to evaluate whether the phosphorylated isoforms of insulin-like growth factor-binding protein-1 (IGFBP-1), a protein produced by the decidua, can be detected in cervical secretions of pregnant women with preterm uterine contractions, and whether their presence predicts an increased risk of preterm delivery. Methods. A prospective analysis of sixty-three women who presented with preterm labor but intact fetal membranes at weeks 22-36+6 days of gestation at the Antenatal clinic at the Department of Obstetrics and Gynecology, Helsinki University Central Hospital. Phosphorylated IGFBP-1 (phIGFBP-1) was measured in cervical swab samples obtained at presentation, using an immunoenzymometric assay. The values ≥10μg/L were considered as positive. In addition, 58 asymptomatic women at the same gestational stage were studied as controls. Multiple logistic regression was applied to control for confounding variables and to obtain adjusted odds ratios. Results. The concentration of... |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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