rA1M-035, a Physicochemically Improved Human Recombinant α1-Microglobulin, Has Therapeutic Effects in Rhabdomyolysis-Induced Acute Kidney Injury

Autor:	Bo Åkerström, Anneli Edström Hägerwall, Sigurbjörg Rutardottir, Lena Erlandsson, Jonas Ahlstedt, Maria Allhorn, Lena Wester Rosenlöf, Magnus Gram, Maria E Johansson
Rok vydání:	2019
Předmět:	0301 basic medicine Heme binding Physiology Clinical Biochemistry Endogeny Reductase Pharmacology Biochemistry law.invention 03 medical and health sciences law medicine Molecular Biology General Environmental Science 030102 biochemistry & molecular biology business.industry Beta-2 microglobulin Acute kidney injury Cell Biology medicine.disease 030104 developmental biology Recombinant DNA General Earth and Planetary Sciences Alpha-1-microglobulin business Rhabdomyolysis
Zdroj:	Antioxidants & Redox Signaling. 30:489-504
ISSN:	1557-7716 1523-0864
DOI:	10.1089/ars.2017.7181
Popis:	Aims: Human α1-microglobulin (A1M) is an endogenous reductase and radical- and heme-binding protein with physiological antioxidant protective functions. Recombinant human A1M (rA1M) has been shown ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::98d2bca59553110a21f6523396811e7e https://doi.org/10.1089/ars.2017.7181 Zobrazit plný text záznamu