Popis: |
The current challenge in drug discovery lies in developing personalized drugs as individual genetic makeup respond differently to a particular drug. There are enough evidences of adverse drug reactions because of genetic response towards drugs in drug therapy. The study of these relations between the human genomics and pharmacogenetics emerged into Pharmacogenomics. There are many publicly accessible pharmacogenomic data repositories having large, rapidly changing and complex data. These databases provide information about the drugs, their adverse reactions, chemical formula, information about metabolic pathways, drug targets, disease for which a particular drug is used etc. None of the existing pharmacogenomic databases carry the complete integrated information and hence there is a need to develop a database which integrates data from all the widely used databases. |