Inhibitors of neuronal and inducible nitric oxide synthase enhance the protective effect of short-term adaptation to hypoxia in Krushinsky-Molodkina rats

Autor:	A. L. Krushinsky, Valentin Reutov, V. E. Dyakonova, V. S. Kuzenkov
Rok vydání:	2015
Předmět:	Nitric oxide synthase chemistry.chemical_compound chemistry biology.protein Moderate hypoxia Hypoxia (environmental) Biology Pharmacology General Agricultural and Biological Sciences General Biochemistry Genetics and Molecular Biology Nitric oxide
Zdroj:	Biology Bulletin. 42:67-73
ISSN:	1608-3059 1062-3590
DOI:	10.1134/s1062359015010057
Popis:	We studied the protective role of nitric oxide (NO) in the adaptation of Krushinsky-Molodkina rats to moderate hypoxia corresponding to 5000 m altitude above sea level. Selective inhibitors of neuronal and inducible NO-synthases (7-nitroindasol and aminoguanidine) have been found to increase significantly the effect of short-term adaptation to hypoxia during the development of stress-induced damage in these rats.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::98a735f12c1af6e0071e32879cee3d7c https://doi.org/10.1134/s1062359015010057 Zobrazit plný text záznamu Plný text ve formátu PDF