In Vitro-in Vivo Correlations — Quo Vadis
| Autor: | S. T. Forgue, T. M. deVries, J. A. Cook, P. G. Welling |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Computer science
Public Health Environmental and Occupational Health Pharmacology (nursing) Pharmacology 030226 pharmacology & pharmacy 01 natural sciences 010104 statistics & probability 03 medical and health sciences 0302 clinical medicine In vivo Drug Guides Pharmacology (medical) Biochemical engineering 0101 mathematics In vitro in vivo |
| Zdroj: | Drug Information Journal. 29:893-902 |
| ISSN: | 0092-8615 |
| DOI: | 10.1177/009286159502900311 |
| Popis: | During the last 25 years, there has been considerable interest in in vitro-in vivo relationships of oral dosage forms. The advantages are obvious in terms of cost, time, and safety. This paper considers the problems involved in establishing in vitro-in vivo relationships, the dimensions of the task, and the different perspectives that apply to in vitro-in vivo correlations. Two examples based on laboratory work on two compounds showing how in vitro data might be used to improve the efficiency and reduce the cost of dosage form development are included. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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