Vitamin A alters the internal viscosity of fragments of limb-bud mesenchyme
| Autor: | T. E. Kwasigroch, D. M. Kochhar |
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| Rok vydání: | 1980 |
| Předmět: | |
| Zdroj: | Development. 59:325-339 |
| ISSN: | 1477-9129 0950-1991 |
| DOI: | 10.1242/dev.59.1.325 |
| Popis: | Two techniques were used to examine the effect of vitamin A compounds (vitamin A acid = retinoic acid and vitamin A acetate) upon the relative strengths of adhesion among mouse limb-bud mesenchymal cells. Treatment with retinoic acid in vivo and with vitamin A acetate in vitro reduced the rate at which the fragments of mesenchyme rounded-up when cultured on a non-adhesive substratum, but these compounds did not alter the behavior of tissues tested in fragment-fusion experiments. These conflicting results indicate that the two tests measure different activities of cells and suggest that treatment with vitamin A alters the property(ies) of cells which regulate the internal viscosity of tissues. |
| Databáze: | OpenAIRE |
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