Facile synthesis of biocompatible polyglycerol hydrogel based on epichlorohydrin
| Autor: | Quanzhu Yang, Lijian Liu, Liqiong Liao, Changjiang Fan, X. G. Yang |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Polymers and Plastics Biocompatibility 02 engineering and technology General Chemistry Carbon-13 NMR 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Surfaces Coatings and Films chemistry.chemical_compound chemistry Dendrimer Polymer chemistry Self-healing hydrogels Materials Chemistry medicine Epichlorohydrin Fourier transform infrared spectroscopy Swelling medicine.symptom 0210 nano-technology Ethylene glycol Nuclear chemistry |
| Zdroj: | Journal of Applied Polymer Science. 133 |
| ISSN: | 0021-8995 |
| DOI: | 10.1002/app.43451 |
| Popis: | A series of hydrophilic polyglycerol (PG) hydrogel was designed and synthesized via one pot with epichlorohydrin (ECH), H2O, and NaOH as the starting materials. The equilibrium swelling ratios of PG hydrogels could be tuned by simply changing the feed amount of NaOH. The gels were characterized by carbon nuclear magnetic resonance (13C NMR) spectroscopy, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy. The As-synthesized PG hydrogels showed temperature-sensitive swelling behaviors. The results of MTT assay suggested that the PG hydrogels prepared by this novel synthesis method showed comparable cytocompatibility with the recognized poly(ethylene glycol) hydrogel. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43451. |
| Databáze: | OpenAIRE |
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