CASE REPORT OF A CHILD DIAGNOSED WITH FIVE SEROTYPES / SEROGROUPS OF S. PNEUMONIAE

Autor:	Viktoria Levterova, Ivan Simeonovski, Nadia Brankova, Magi Ivanova, Ivva Philipova, Mariya Malcheva
Rok vydání:	2023
Předmět:	Microbiology (medical) Infectious Diseases General Immunology and Microbiology
Zdroj:	PROBLEMS of Infectious and Parasitic Diseases. 50:5-7
ISSN:	2815-2808 0204-9155
DOI:	10.58395/pipd.v50i2.87
Popis:	Streptococcus pneumoniae is one of the most common causes of widespread diseases. Pneumococci colonize asymptomatically the nasopharynx in children and could be responsible for severe, life-threatening illnesses such as pneumonia, sepsis and meningitis. The case report shows co-colonisation in two-year-old child vaccinated with the 10-valent pneumococcal conjugate vaccine (PCV-10) suffering from recurring catarrh and found to carry 5 serotypes S. pneumoniae. The strains have been detected and typed using molecular methods: real-time polymerase chain reaction (real-time PCR) and allelic hybridization. Monitoring S. pneumoniae colonization of human mucosa is crucial to reduce the likelihood of severe invasive pneumococcal diseases such as meningitis, pneumonia or otitis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::98711630630c845f915b670d278d834f https://doi.org/10.58395/pipd.v50i2.87 Zobrazit plný text záznamu